I ran into this issue while booting up my server. Luckily it was easy to fix after doing a bit of research 🙂
Problem: kernel panic-not syncing: VFS: unable to mount root fs on unknown block(0,0)
Solution: remove old linux kernels, your /boot drive is out of space
- boot to grub and click on “Advanced options”
- Select a previous kernel (should boot fine)
- login and enter command
- $ df
- See if your /boot directory is 100% used
- Remove old linux kernels
- $ sudo apt-get autoremove
Sources: